Unit II: Medicinal Chemistry

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• Anti-anginal:
• Vasodilators: Amyl nitrite, Nitroglycerin*, Pentaerythritol tetranitrate, Isosorbide dinitrite*, Dipyridamole.
• Calcium channel blockers: Verapamil, Bepridil hydrochloride, Diltiazem hydrochloride, Nifedipine, Amlodipine, Felodipine, Nicardipine, Nimodipine.
• Diuretics:Carbonic anhydrase inhibitors: Acetazolamide*, Methazolamide,Dichlorphenamide. Thiazides: Chlorthiazide*, Hydrochlorothiazide, Hydroflumethiazide,Cyclothiazide,
• Loop diuretics: Furosemide*, Bumetanide, Ethacrynic acid.Potassium sparing Diuretics: Spironolactone, Triamterene, Amiloride.
• Osmotic Diuretics: MannitolAnti-hypertensive Agents: Timolol, Captopril, Lisinopril, Enalapril, Benazeprilhydrochloride, Quinapril hydrochloride, Methyldopate hydrochloride,* Clonidine hydrochloride, Guanethidine monosulphate, Guanabenz acetate, Sodium
  nitroprusside, Diazoxide, Minoxidil, Reserpine, Hydralazine hydrochloride.