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Medicinal Chemistry I PDF Notes
Unit I
- Introduction to Medicinal Chemistry
- History and development of medicinal chemistry
- Physicochemical properties in relation to biological action
- Drug metabolism
Unit II
- Drugs acting on Autonomic Nervous System
- Adrenergic Neurotransmitters
- Sympathomimetic agents: SAR of Sympathomimetic agents
- Adrenergic Antagonists: Alpha-adrenergic blockers, Beta-adrenergic blockers:
Unit III
- Cholinergic neurotransmitters
- Parasympathomimetic agents: SAR of Parasympathomimetic agents
- Direct acting agents
- Indirect acting/ Cholinesterase inhibitors (Reversible & Irreversible)
- Cholinesterase reactivator
- Cholinergic Blocking Agents: SAR of cholinolytic agent
- Solanaceous alkaloids and analogues
- Synthetic cholinergic blocking agent
Unit IV
- Drugs acting on Central Nervous System
- A. Sedatives and Hypnotics: Benzodiazepines, Barbiturates, Miscellaneous
- B. Antipsychotics: Phenothiazines, Ring Analogues of Phenothiazeines, Fluro butyrophenones, Beta amino ketone, Beta amino ketone
- C. Anticonvulsants: Barbiturates, Monoacylureas, Benzodiazepines, Miscellaneous
Unit V
- Drugs acting on Central Nervous System
- General anaesthetics: Inhalation anaesthetics, Ultra short-acting barbiturates, Dissociative anaesthetics
- Narcotic and non-narcotic analgesics: Morphine and related drugs, Narcotic antagonists, Anti-inflammatory agents
Pharmaceutical Organic Chemistry III PDF Notes
Unit IV
- Synthesis, reactions and medicinal uses of the following compounds/derivatives: Pyrazole, Imidazole, Oxazole and Thiazole. Pyridine, Quinoline, Isoquinoline, Acridine and Indole. Basicity of pyridine
Pharmacology I PDF Notes
Unit II
- Pharmacodynamics
- Adverse drug reaction
- Drug interactions
- Drug discovery and clinical evaluation of new drugs
Unit IV
- a. Neurohumoral transmission in the C.N.S.special emphasis on the importance of various neurotransmitters like with GABA, Glutamate, Glycine, serotonin, and dopamine.
- b. General anaesthetics and pre-anaesthetics.
- c. Sedatives, hypnotics and centrally acting muscle relaxants.
- d. Anti-epileptics
- e. Alcohols and disulfiram
Unit V
- a. Psychopharmacological agents: Antipsychotics, antidepressants, anti-anxiety agents, anti-manics and hallucinogens.
- b. Drugs used in Parkinson’s disease and Alzheimer’s disease.
- c. CNS stimulants and nootropics.
- d. Opioid analgesics and antagonists
- e. Drug addiction, drug abuse, tolerance and dependence.
Pharmacognosy and Phytochemistry I PDF Notes
Unit I
- Introduction to Pharmacognosy
- Classification of drugs
- Quality control of Drugs of Natural Origin
Unit II
- Cultivation, Collection, Processing and storage of drugs of natural origin
- Conservation of medicinal plants
Unit IV
- Pharmacognosy in various systems of medicine
- Introduction to secondary metabolites
Unit V
- Plant Products
- Primary metabolites
- Carbohydrates
- Proteins and Enzymes
- Lipids(Waxes, fats, fixed oils)
- Marine Drugs
Physical Pharmaceutics II PDF Notes
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