Get Latest Updates About Pharmacy Notes, Books and Many More
Aim To determine the percentage purity of a given sample of Metronidazole tablet. Principle A substance with very weak acid or basic property does not give a sharp endpoint in an aqueous solution can be titrated with non-aqueous solvents. Non-aqueous…
Aim To determine the percentage purity of a given sample of Isonicotinic acid hydrazide tablet. Principle Isonicotinic acid hydrazide/ isoniazid is an anti-tubercular drug. It is assayed by the direct titration of Potassium bromate with the addition of potassium bromide…
Aim To prepare and submit hexamine from formaldehyde and calculate its Percentage Yield. Principle Hexamine is a heterocyclic organic compound (CH2)6N4. It has a symmetrical tetrahedral cage-like structure. It is prepared by a condensationreaction between formaldehyde and ammonia. Reaction Requirements…
Aim To prepare and submit tolbutamide from p-toluene sulfonamide and calculate its percentage yield. Principle The synthesis of tolbutamide involves the addition reaction of p-toluene sulfonamide and butyl isocyanate in the presence of triethylamine andtetrahydrofuran. Reaction Requirements p-Toluene Sulfonamide –…
Aim To Prepare and submit chlorobutanol from acetone and calculate the Percentage Yield. Principle Chlorbutanol is also known as Chloroketone. It is a trichloro derivative of tertiary butyl alcohol. It is prepared by combination with acetone andchloroform in the presence…
Aim To Synthesis and submit Synthesis of 7- Hydroxy -4- methyl coumarin. Principle A general synthesis of coumarins involves the interaction of a phenol with a β- ketoester in presence of an acid condensing agent (Pechmannreaction). Concentrated sulphuric acid is…
Aim To synthesis and submit sulphanilamide from p-acetamido benzene sulphanilamide and calculate its percentage yield. Principle Sulphanilamide can be prepared by the reaction of P-acetamido benzene sulphanilamide with Hydrochloric acid or ammonium carbonate. The acetamido groups are easily undergoing acid…
Aim: To study the local anaesthetic property of procaine HCL using nerve block anaesthesia byfrog foot withdrawal method. Principle: Local anaesthetics reversibly block impulse conduction along nerve axons and excitable membranes. Their action is used to produce local or regional…
Aim: To study the anxiolytic activity of diazepam in mice using elevated zero mazes. Principle: The elevated zero maze test is a behavioural test of anxiety based on the naturalisticthe tendency of rodents to avoid open and elevated areas. It…
Aim: To study drug (phenothiazines)- induced catatonia (extrapyramidal side effect in rats. to study the anticatatonic (antiparkinsonian) effect of scopolamine. Principle: Phenothiazine and butyrophenone type antipsychotic drugs are known to produce extrapyramidal side-effects in man these effects, such as akinesia,…